BDBM50006980 (3-Phenyl-propyl)-(1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL25858

SMILES C(CNC1CCc2ccccc2C1)Cc1ccccc1

InChI Key InChIKey=CEMUKLXXZBFFNQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006980   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  13nMAssay Description:Binding affinity at [3H]8-OH-DPAT-Labeled 5-hydroxytryptamine 1A receptor sites in rat brain hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  13nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006980(CHEMBL25858 | (3-Phenyl-propyl)-(1,2,3,4-tetrahydr...)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed