BDBM50006975 CHEMBL19802::US11999676, Compound 11::[2-(4-Bromo-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine

SMILES CC(Cc1ccc(Br)cc1)NCCCc1ccccc1

InChI Key InChIKey=TWSHNGSMVLDKOH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006975   

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)
Affinity DataKi:  12nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)
Affinity DataKi:  700nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In DepthDetails
US Patent