BDBM50006607 CHEMBL3235465::US9604926, Compound SN-79::US9724435, SN-79

SMILES CC(=O)c1ccc2n(CCCCN3CCN(CC3)c3ccc(F)cc3)c(=O)oc2c1

InChI Key InChIKey=VGDFDVKDWFJQHD-UHFFFAOYSA-N

Data  18 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50006607   

TargetSigma intracellular receptor 2(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  6.06nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  6.06nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
Washington University

Curated by ChEMBL
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from sigma-1 opioid receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  159nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  159nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetTransporter(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  177nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  177nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  320nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  2.62E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  2.62E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
Washington University

Curated by ChEMBL
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi: >1.00E+5nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50006607(CHEMBL3235465 | US9604926, Compound SN-79 | US9724...)
Affinity DataKi:  1.00E+5nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent