BDBM50005535 (1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

SMILES COC(=O)[C@@H]1[C@H]2CCC(C[C@H]1OC(=O)c1ccccc1)N2C

InChI Key InChIKey=ZPUCINDJVBIVPJ-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50005535   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 384nMAssay Description:Inhibition of [3H]BTCP binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatal membrane dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 317nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 690nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 640nMAssay Description:Inhibition of [3H]mazindol binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 525nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005535((1R,2R,3R,8R)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed