BDBM50005340 2-Butyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-benzoimidazole::2-Butyl-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-benzoimidazole::CHEMBL7641

SMILES CCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=IFVAHIKNRDQTNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50005340   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005340(CHEMBL7641 | 2-Butyl-1-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 96nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1/Type-2 angiotensin II receptor(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50005340(CHEMBL7641 | 2-Butyl-1-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 96nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2019
Entry Details Article
PubMed
TargetType-1/Type-2 angiotensin II receptor(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50005340(CHEMBL7641 | 2-Butyl-1-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 96nMAssay Description:Displacement of monoiodinated angiotensin II from guinea-pig adrenal gland angiotensin II receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details

LigandPNGBDBM50005340(CHEMBL7641 | 2-Butyl-1-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 900nMAssay Description:Displacement of [125I]angiotensin 2 from type-1 angiotensin 2 receptor in Bos taurus (bovine) adrenal cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article