BDBM50005337 CHEMBL1276317

SMILES OCC(O)CO\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccccc12

InChI Key InChIKey=ZWXBEUSAAVHLFW-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50005337   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 430nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 75nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 210nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 540nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 950nMAssay Description:Inhibition of c-SRC in human MDA-MB-468 cells in presence of [gamma-32P]ATP and ATP by immunoprecipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 950nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant c-Src (unknown origin) incubated for 120 mins in presence of [33P]-ATP by hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed