BDBM50005044 (2R,4S)-5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidin-1-yl)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidin-1-yl)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL58663

SMILES OC(=O)[C@H]1C[C@H](N2CCN(C2=O)c2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key InChIKey=MCDUTXFQVFQCEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005044   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005044(CHEMBL58663 | (2R,4S)-5,7-Dichloro-4-(2-oxo-3-phen...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]- glycine binding to N-methyl-D-aspartate glutamate receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005044(CHEMBL58663 | (2R,4S)-5,7-Dichloro-4-(2-oxo-3-phen...)
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed