BDBM50004586 8-Dicyclopropylmethyl-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL313780

SMILES CC(C)Cn1c2nc([nH]c2c(=O)n(C)c1=O)C(C1CC1)C1CC1

InChI Key InChIKey=GKLKHJBKPRFKON-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50004586   

TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  12nMAssay Description:Binding affinity carried out with [3H]cyclohexyladenosine in guinea pig forebrain membranes against adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  12nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  12nMAssay Description:Binding affinity against Adenosine A1 receptor from guinea pig forebrain membranes by N6-[3H]- cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  410nMAssay Description:Binding affinity at Adenosine A2 receptor from rat striatal membranes by N-[3H] ethyladenosin-5'- uronamide displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  410nMAssay Description:Binding affinity carried out with [3H]5'-(N-ethylcarbamoyl)-adenosine in the presence of 50 nM cyclopentyladenosine in rat striatal membranes against...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004586(CHEMBL313780 | 8-Dicyclopropylmethyl-3-isobutyl-1-...)
Affinity DataKi:  410nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed