BDBM50004584 (8-Chloro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-cyclopentyl-amine::CHEMBL72669

SMILES FC(F)(F)c1nnc2c(NC3CCCC3)nc3ccc(Cl)cc3n12

InChI Key InChIKey=BZULZOAWPMZGRT-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004584   

TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataIC50: 2.10E+3nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cortical membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataKi:  28nMAssay Description:Binding affinity for Adenosine A1 receptor using [3H]- CHA or [3H]- PIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataKi:  36nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataKi:  710nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 5...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004584(CHEMBL72669 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity towards adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed