BDBM50004573 1,3-Dibutyl-8-dicyclopropylmethyl-3,7-dihydro-purine-2,6-dione::CHEMBL318537

SMILES CCCCn1c2nc([nH]c2c(=O)n(CCCC)c1=O)C(C1CC1)C1CC1

InChI Key InChIKey=GMRWZHXYIPEMGX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50004573   

TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004573(CHEMBL318537 | 1,3-Dibutyl-8-dicyclopropylmethyl-3...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity carried out with [3H]cyclohexyladenosine in guinea pig forebrain membranes against adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004573(CHEMBL318537 | 1,3-Dibutyl-8-dicyclopropylmethyl-3...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004573(CHEMBL318537 | 1,3-Dibutyl-8-dicyclopropylmethyl-3...)
Affinity DataKi:  440nMAssay Description:Binding affinity carried out with [3H]5'-(N-ethylcarbamoyl)-adenosine in the presence of 50 nM cyclopentyladenosine in rat striatal membranes against...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004573(CHEMBL318537 | 1,3-Dibutyl-8-dicyclopropylmethyl-3...)
Affinity DataKi:  440nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed