BDBM50004187 ((S)-1-{Indan-2-yl-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-carbamic acid benzyl ester::(1-{Indan-2-yl-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-carbamic acid benzyl ester::CHEMBL264180

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C1Cc2ccccc2C1

InChI Key InChIKey=CZNYUGWWZNZONF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004187   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004187((1-{Indan-2-yl-[(3,3,3-trifluoro-1-isopropyl-2-oxo...)
Affinity DataIC50: 365nMpH: 7.5Assay Description:Inhibitory activity against human leukocyte elastase (HLE) at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004187((1-{Indan-2-yl-[(3,3,3-trifluoro-1-isopropyl-2-oxo...)
Affinity DataIC50: 365nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004187((1-{Indan-2-yl-[(3,3,3-trifluoro-1-isopropyl-2-oxo...)
Affinity DataIC50: 365nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed