BDBM50003755 (2R)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(pyrrolidin-1-yl)cyclohexan-1-amine::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-cyclohexyl)-amine
SMILES CN(CCc1ccc(Cl)c(Cl)c1)[C@@H]1CCCC[C@H]1N1CCCC1
InChI Key InChIKey=SRRUPDPTTGLICG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50003755
Affinity DataEC50: 57nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 455nMAssay Description:Binding affinity for sigma receptor using [3H](+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 538nMAssay Description:Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H](+)-3-PPP as radioligand in guinea pig brainMore data for this Ligand-Target Pair