BDBM50003740 (Lactone IIa)N-[4-(2-Methylene-6-oxo-tetrahydro-pyran-4-yl)-phenyl]-guanidine::CHEMBL134926::amino{[4-(2-methylene-6-oxotetrahydro-2H-pyran-4-yl)phenyl]amino}methaniminium

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(cc1)-[#6]-1-[#6]-[#6](=[#6])-[#8]-[#6](=O)-[#6]-1

InChI Key InChIKey=DFBSEVWINCQMTQ-UHFFFAOYSA-N

Data  2 KI  4 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50003740   

TargetSerine protease 1(Bovine)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKon:  0.0000330M-1s-1Assay Description:Decylation rate constant against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKon:  0.000150M-1s-1Assay Description:Decylation rate constant against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKon:  0.0000330M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKon:  0.000150M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKi:  120nMAssay Description:Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003740(CHEMBL134926 | amino{[4-(2-methylene-6-oxotetrahyd...)
Affinity DataKi:  9.40E+3nMAssay Description:Compound was tested for its binding affinity against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed