BDBM50003448 (2Z)-3-[(acetyloxy)(benzyl)amino]-1-(4-fluorophenyl)prop-2-en-1-one::1-(4-fluorophenyl)-3-benzyl-3-acetyloxyamino-propenone::CHEMBL11807

SMILES CC(=O)ON(Cc1ccccc1)C=CC(=O)c1ccc(F)cc1

InChI Key InChIKey=GPZMNMSAHDMJBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003448   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003448(1-(4-fluorophenyl)-3-benzyl-3-acetyloxyamino-prope...)
Affinity DataIC50: 2.50E+4nMAssay Description:inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003448(1-(4-fluorophenyl)-3-benzyl-3-acetyloxyamino-prope...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 5-Lipoxygenase of rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003448(1-(4-fluorophenyl)-3-benzyl-3-acetyloxyamino-prope...)
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was evaluated for inhibition against Phospholipase A2 of Croatalus adamanteusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50003448(1-(4-fluorophenyl)-3-benzyl-3-acetyloxyamino-prope...)
Affinity DataIC50: 7.50E+5nMAssay Description:Compound was evaluated for inhibition against cyclooxygenase of bovine seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article