BDBM50003446 (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-propenone::3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-propenone::CHEMBL11308

SMILES ON(Cc1ccccc1)\C=C/C(=O)c1ccc(F)cc1

InChI Key InChIKey=ZUJYYCSNLSCOIM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003446   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003446(CHEMBL11308 | (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fl...)
Affinity DataIC50: 150nMAssay Description:inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50003446(CHEMBL11308 | (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was evaluated for inhibition against Phospholipase A2 of Croatalus adamanteusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003446(CHEMBL11308 | (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-Lipoxygenase of rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50003446(CHEMBL11308 | (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fl...)
Affinity DataIC50: 7.50E+5nMAssay Description:Compound was evaluated for inhibition against cyclooxygenase of bovine seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article