BDBM50003040 CHEMBL122860::Dimethyl-[2-(1,6,7,8-tetrahydro-pyrano[2,3-f]indol-3-yl)-ethyl]-amine

SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12

InChI Key InChIKey=JLWIAKOXJGKMDU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50003040   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 5.90E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 920nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed