BDBM50002473 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanoic acid::CHEMBL41743

SMILES NCCCC(NC(=O)c1ccc(NCc2cnc3nc(N)[nH]c(=O)c3n2)cc1)C(O)=O

InChI Key InChIKey=ODGLNGSSLASZFM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002473   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity for hog liver Folyl-polyglutamate synthase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed