BDBM50002268 1-Benzyl-4-(3-phenyl-propoxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL337810::CHEMBL80656

SMILES C(COCC1CCN(Cc2ccccc2)CC1)Cc1ccccc1

InChI Key InChIKey=CSHFTPUNJFOMTD-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50002268   

TargetD(2) dopamine receptor(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataIC50: 839nMAssay Description:The compound was tested in vitro for its binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataKi:  27nMAssay Description:Binding affinity towards sigma receptor using [3H](+)-SKF-10047 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataKi:  260nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50002268(CHEMBL337810 | CHEMBL80656 | 1-Benzyl-4-(3-phenyl-...)
Affinity DataKi:  554nMAssay Description:Binding affinity towards Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article