BDBM50002171 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL64344

SMILES Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=WOQPWODQIGGKJL-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50002171   

Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataIC50: 27nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataIC50: 7.5nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataIC50: 71nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataIC50: 51nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataIC50: 90nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002171(CHEMBL64344 | 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydr...)
Affinity DataKi:  15nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed