BDBM50002164 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole::CHEMBL59335

SMILES C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1

InChI Key InChIKey=JHLJHQQFPBTTJE-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50002164   

Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataIC50: 25nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataIC50: 110nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataIC50: 45nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataIC50: 100nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002164(CHEMBL59335 | 3-[4-(4-Phenyl-piperidin-1-yl)-butyl...)
Affinity DataKi: >100nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed