BDBM50001709 4-cyclopropylmethyl-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,14,17-triol::CHEMBL140278::CHEMBL558140::Naltrexone-6-beta-ol
SMILES O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45
InChI Key InChIKey=JLVNEHKORQFVQJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50001709
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Inverse agonist activity at human recombinant mu opioid receptor expressed in CHO cells after 3 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of opioid receptor mu by displacing 1 nM [3H]DAGO in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Opioid receptor delta 1 by displacing 1 nM [3H]DPDPE in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of opioid receptor kappa by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Tested for the binding affinity against the Mu opioid receptor in guinea pig brain using [3H]-DAMGOMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Tested for the binding affinity against the Delta opioid receptor in guinea pig brain using [3H]DPDPEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Tested for the binding affinity against the Kappa opioid receptor in guinea pig brain using [3H]U-69593More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 213nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair