BDBM50001044 (1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-4-ol::3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL74019

SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC=C

InChI Key InChIKey=LGQCVMYAEFTEFN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50001044   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured after 120 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi:  157nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi:  169nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-Diprenorphine from MOR receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-Diprenorphine from DOR receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-U69593 from KOR receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001044((1S,9S,13S)-10-allyl-1,13-dimethyl-10-azatricyclo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DAMGO from human MOR receptor assessed as inhibition constant by cheng-prusoff equation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed