BDBM499670 US11020397, Compound Formula-(IIaa)

SMILES CSc1nc(O)c(C(=O)Nc2ccc(-c3c[nH]nn3)c(F)c2F)c(=O)[nH]1

InChI Key InChIKey=CGSZLUKNGUPHOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 499670   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM499670(US11020397, Compound Formula-(IIaa))
Affinity DataIC50: 9.00E+4nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499670(US11020397, Compound Formula-(IIaa))
Affinity DataIC50: 0.103nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent