BDBM49829 (2-fluorophenyl)(5-(2-(methylamino)thiazol-4-yl)indolin-1-yl)methanone (Compound 1)::(2-fluorophenyl)-[5-[2-(methylamino)-1,3-thiazol-4-yl]-2,3-dihydroindol-1-yl]methanone::(2-fluorophenyl)-[5-[2-(methylamino)-4-thiazolyl]-2,3-dihydroindol-1-yl]methanone::(2-fluorophenyl)-[5-[2-(methylamino)thiazol-4-yl]indolin-1-yl]methanone::MLS000718316::SMR000290584::cid_1450294

SMILES CNc1nc(cs1)-c1ccc2N(CCc2c1)C(=O)c1ccccc1F

InChI Key InChIKey=DAKHCIUKYFQQEU-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49829   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49829(SMR000290584 | (2-fluorophenyl)-[5-[2-(methylamino...)
Affinity DataEC50:  2.66E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetNeuropilin-1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49829(SMR000290584 | (2-fluorophenyl)-[5-[2-(methylamino...)
Affinity DataIC50: 9.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSerine/threonine-protein kinase WNK1 [198-401](Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM49829(SMR000290584 | (2-fluorophenyl)-[5-[2-(methylamino...)
Affinity DataIC50: 5.70E+3nMAssay Description:For hit validation, eight compound replicates were made from the original stock dilution plates. The Cybi-WellTM dispenser was used to prepare 1.5 &#...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [198-401](Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM49829(SMR000290584 | (2-fluorophenyl)-[5-[2-(methylamino...)
Affinity DataIC50: 8.80E+3nMAssay Description:For hit validation, eight compound replicates were made from the original stock dilution plates. The Cybi-WellTM dispenser was used to prepare 1.5 &#...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed