BDBM496979 US10995099, Example 69

SMILES COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(C2CCC2C(O)=O)c1=O)-c1ncco1)OC1CCOCC1

InChI Key InChIKey=GZAVNSJWXYOMFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 496979   

TargetAcetyl-CoA carboxylase 1(Human)
Nanjing Ruijie Pharmatech

US Patent
LigandPNGBDBM496979(US10995099, Example 69)
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Nanjing Ruijie Pharmatech

US Patent
LigandPNGBDBM496979(US10995099, Example 69)
Affinity DataIC50: 10nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
In DepthDetails
US Patent