BDBM495283 N-(5-(4-((R)-1-((S)-2-methyl-2,3-dihydrobenzofuran-6-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide and N-(5-(4-((S)-1-((S)-2-methyl-2,3-dihydrobenzofuran-6-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide::US10995090, No 16::US10995090, No 17

SMILES CC(N1CCN(CC1)c1nnc(NC(C)=O)s1)c1ccc2C[C@H](C)Oc2c1

InChI Key InChIKey=WZYIZWQWRGLUGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495283   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM495283(US10995090, No 16 | N-(5-(4-((R)-1-((S)-2-methyl-2...)
Affinity DataIC50: 600nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in Mcllvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
Go to US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM495283(US10995090, No 16 | N-(5-(4-((R)-1-((S)-2-methyl-2...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in Mcllvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
Go to US Patent