BDBM492623 US10980809, Example 19
SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)c(F)c3)c2c2OCCOc12
InChI Key InChIKey=INBWVBTWAPTACH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 492623
TargetVascular endothelial growth factor receptor 2(Human)
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: 50nMAssay Description:1. Dilution of the compound: a total of 12 concentrations were obtained using a 4-fold gradient dilution from the highest concentration of 10000 nM (...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: 50nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair