BDBM492589 6-Amino-4-(5-isopropyl-4-methoxy-2-methylphenyl)-3-(thiophen-2-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::US10980781, Compound 6r::US11617738, Compound 6r

SMILES COc1cc(C)c(cc1C(C)C)C1c2c(OC(N)=C1C#N)n[nH]c2-c1cccs1

InChI Key InChIKey=SYPHZAGYJPTCNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492589   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492589(6-Amino-4-(5-isopropyl-4-methoxy-2-methylphenyl)-3...)
Affinity DataIC50: 1.40E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492589(6-Amino-4-(5-isopropyl-4-methoxy-2-methylphenyl)-3...)
Affinity DataIC50: 1.40E+3nMAssay Description:The percent inhibition of USP7 at 100 μM of each compound was determined prior to the determination of IC50 values. The final concentration of s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent