BDBM49246 (E)-1-(3-methoxyphenyl)-3-[(5-methyl-2-oxidanyl-phenyl)amino]prop-2-en-1-one::(E)-3-(2-hydroxy-5-methyl-anilino)-1-(3-methoxyphenyl)prop-2-en-1-one::(E)-3-(2-hydroxy-5-methylanilino)-1-(3-methoxyphenyl)-2-propen-1-one::(E)-3-(2-hydroxy-5-methylanilino)-1-(3-methoxyphenyl)prop-2-en-1-one::3-[(2-hydroxy-5-methylphenyl)amino]-1-(3-methoxyphenyl)-2-propen-1-one::MLS000088060::SMR000072274::cid_2186107

SMILES COc1cccc(c1)C(=O)CC=Nc1cc(C)ccc1O

InChI Key InChIKey=UIJGBRZBYPHSNM-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 49246   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49246(MLS000088060 | SMR000072274 | (E)-3-(2-hydroxy-5-m...)
Affinity DataEC50:  5.51E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetE3 ubiquitin-protein ligase XIAP(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49246(MLS000088060 | SMR000072274 | (E)-3-(2-hydroxy-5-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM49246(MLS000088060 | SMR000072274 | (E)-3-(2-hydroxy-5-m...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay