BDBM48984 MLS000107876::SMR000103840::US11718589, Compound 1a::[5-(4-methoxyphenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-(1-piperidinyl)methanone::[5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-yl-methanone::[5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone::[5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidino-methanone::cid_1244790

SMILES COc1ccc(cc1)-c1cc(n2nc(cc2n1)C(=O)N1CCCCC1)C(F)(F)F

InChI Key InChIKey=CFLAIXWXKXQQEB-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 48984   

TargetD(1B) dopamine receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48984(cid_1244790 | [5-(4-methoxyphenyl)-7-(trifluoromet...)
Affinity DataEC50:  0.0216nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetD(1A) dopamine receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48984(cid_1244790 | [5-(4-methoxyphenyl)-7-(trifluoromet...)
Affinity DataEC50:  0.0171nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM48984(cid_1244790 | [5-(4-methoxyphenyl)-7-(trifluoromet...)
Affinity DataIC50: 24nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent