BDBM489782 US10995099, Example 26::US10995099, Example 37

SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(c1=O)C1(CCC1)C(O)=O)-c1ncco1)OC1CCOCC1

InChI Key InChIKey=RSTRSTLVECXVQL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 489782   

TargetAcetyl-CoA carboxylase 2(Human)
Nanjing Ruijie Pharmatech

US Patent
LigandPNGBDBM489782(US10995099, Example 37 | US10995099, Example 26)
Affinity DataIC50: 10nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Nanjing Ruijie Pharmatech

US Patent
LigandPNGBDBM489782(US10995099, Example 37 | US10995099, Example 26)
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Nanjing Ruijie Pharmatech

US Patent
LigandPNGBDBM489782(US10995099, Example 37 | US10995099, Example 26)
Affinity DataIC50: 10nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
In DepthDetails
US Patent