BDBM4891 3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-[4-Methyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid::3-substituted indolin-2-one 11e::SU5402 analog 11e

SMILES Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2cc(ccc12)-c1ccccc1

InChI Key InChIKey=CEFJMJRPRONXNH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4891   

LigandPNGBDBM4891(3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2005
Entry Details Article
PubMed
LigandPNGBDBM4891(3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...)
Affinity DataIC50: 1.05E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2005
Entry Details Article
PubMed
LigandPNGBDBM4891(3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...)
Affinity DataIC50: 160nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2005
Entry Details Article
PubMed
LigandPNGBDBM4891(3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...)
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2005
Entry Details Article
PubMed