BDBM488317 US10954240, Example 19

SMILES CCn1cc(cn1)-c1ccc2cnn(-c3ccnc(c3)N3CCOCC3)c2c1

InChI Key InChIKey=SQEXHRAAZAWFTL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488317   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S](Human)
Merck Sharp & Dohme

US Patent

LigandBDBM488317(US10954240, Example 19)Copy SMILESCopy InChI

Affinity DataIC50: 128nMAssay Description:LRRK2 Km ATP LanthaScreen Assaya) 400 nl of a 1:2.15 serial dilution of test compound (98 μM top assay concentration) is spotted via Labcyte Ech...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/28/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL