BDBM4881 1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylmethyl)phthalazine::CGP79787 Analog 66::N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES Fc1cc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc(c1)C(F)(F)F

InChI Key InChIKey=FZROGUOMLPOFBV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4881   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4881(1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylm...)
Affinity DataIC50: 350nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4881(1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylm...)
Affinity DataIC50: 200nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4881(1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylm...)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4881(1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylm...)
Affinity DataIC50: 1.00E+4nMAssay Description:The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed