BDBM488059 N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4-(1- ((3-methyloxetan-3- yl)methyl)-3-(pyridin- 3-yl))-1H-pyrazol-4- yl)pyrimidin-2-amine::US10954216, Example 77

SMILES COCCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(CC3(C)COC3)nc2-c2cccnc2)cc1

InChI Key InChIKey=LQGYRTITIFLAJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488059   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488059(N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...)
Affinity DataIC50: 7.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
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Date in BDB:
9/28/2021
Entry Details
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