BDBM488053 N-(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2-yl)-2- methyl-1,2,3,4- tetrahydroisoquinolin- 6-amine::US10954216, Example 64

SMILES COCCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc3CN(C)CCc3c2)n1

InChI Key InChIKey=SQXFNOJGZONCGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488053   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488053(N-(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- py...)
Affinity DataIC50: 12.6nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
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Date in BDB:
9/28/2021
Entry Details
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