BDBM488051 1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2- yl)amino)-1H-pyrazol- 1-yl)piperidin-1-yl)-2- methylpropan-2-ol::US10954216, Example 54

SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2cnn(c2)C2CCN(CC(C)(C)O)CC2)n1

InChI Key InChIKey=YSNBDRSAUGKJEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488051   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488051(1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 11.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
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Date in BDB:
9/28/2021
Entry Details
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