BDBM488041 4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyrazol-4-yl)-N-(4-(4- (2-methoxyethyl)- piperazin-1- yl)phenyl)pyrimidin-2- amine::US10954216, Example 37

SMILES COCCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(CCOC)nc2-c2cccnc2)cc1

InChI Key InChIKey=HEMGSPAHKAXCSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488041   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488041(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyraz...)
Affinity DataIC50: 7.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandPNGBDBM488041(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyraz...)
Affinity DataIC50: 10.4nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In DepthDetails
US Patent