BDBM4878 1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthalazine::CGP79787 Analog 63::N-(3,5-dimethylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES Cc1cc(C)cc(Nc2nnc(Cc3ccncc3)c3ccccc23)c1

InChI Key InChIKey=QQJMEMQSYAOKGB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4878   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4878(1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthala...)
Affinity DataIC50: 150nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4878(1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthala...)
Affinity DataIC50: 40nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4878(1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthala...)
Affinity DataIC50: 800nMAssay Description:The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4878(1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthala...)
Affinity DataIC50: 2.00E+3nMAssay Description:The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed