BDBM486352 US10947222, Example 1

SMILES CC1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(cn(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl

InChI Key InChIKey=GTVCYCZTPJZBKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486352   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486352(US10947222, Example 1)
Affinity DataIC50: 8.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent