BDBM4861 CGP79787 Analog 52::N-(4-chlorophenyl)-4-[1-(pyridin-4-yl)ethyl]phthalazin-1-amine::rac-1-(4-Chloroanilino)-4-[1-(4-pyridyl)ethyl]phthalazine

SMILES CC(c1ccncc1)c1nnc(Nc2ccc(Cl)cc2)c2ccccc12

InChI Key InChIKey=AFECIUCRUIZUKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4861   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4861(rac-1-(4-Chloroanilino)-4-[1-(4-pyridyl)ethyl]phth...)
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4861(rac-1-(4-Chloroanilino)-4-[1-(4-pyridyl)ethyl]phth...)
Affinity DataIC50: 210nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed