BDBM4858 1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]-phthalazine::CGP79787 Analog 43::N-(4-chlorophenyl)-4-[(2-methylpyridin-4-yl)methyl]phthalazin-1-amine

SMILES Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)ccn1

InChI Key InChIKey=ZQIINWWMLNWZKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4858   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4858(1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]...)
Affinity DataIC50: 620nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4858(1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]...)
Affinity DataIC50: 240nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed