BDBM485697 N-hydroxylethyl-4-(2-bromo-3-(3,4-dimethoxyphenyl)benzyloxy)-2-(3-cyanobenzyl oxy) benzylamine::US10941129, Example 11

SMILES COc1ccc(cc1OC)-c1cccc(COc2ccc(CNCCO)c(OCc3cccc(c3)C#N)c2)c1Br

InChI Key InChIKey=OSKCJUFODPFSHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485697   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485697(N-hydroxylethyl-4-(2-bromo-3-(3,4-dimethoxyphenyl)...)
Affinity DataIC50: 7.87E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent