BDBM485690 N-hydroxylethyl-4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-cyanobenzyloxy) benzylamine::US10941129, Example 21

SMILES OCCNCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1cccc(c1)C#N

InChI Key InChIKey=WFKSDDBJJFYOET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485690   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485690(N-hydroxylethyl-4-(2-bromo-3-phenylbenzyloxy)-5-ch...)
Affinity DataIC50: 5.29nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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