BDBM485654 US10940139, Example 02511::US11000515, Compound TABLE 7.62::US11213515, TABLE 7.62::US11541041, Compound Table 7.41
SMILES CC(Oc1cccc(c1)C#N)C(=O)Nc1nnc([nH]1)-c1ccccn1
InChI Key InChIKey=QGUIYCYMANRFNN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 485654
Affinity DataIC50: 5.00E+3nMAssay Description:Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) 1 mM MgCl2 1 mM DTT. KRas G12D mutant protein was expressed as a His-tagged protein. Purified His...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) 1 mM MgCl2 1 mM DTT. KRas G12D mutant protein was expressed as a His-tagged protein. Purified His...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) 1 mM MgCl2 1 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I:50 mM Tris, pH 7.5150 mM NaCl (optional)1 mM MgCl21 mM DTT...More data for this Ligand-Target Pair