BDBM4854 1-(4-Chlorophenylsulfanyl)-4-(4-pyridylmethyl)phthalazine::1-[(4-chlorophenyl)sulfanyl]-4-(pyridin-4-ylmethyl)phthalazine::CGP79787 Analog 39

SMILES Clc1ccc(Sc2nnc(Cc3ccncc3)c3ccccc23)cc1

InChI Key InChIKey=DUSBNRXTCYVZOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4854   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4854(1-[(4-chlorophenyl)sulfanyl]-4-(pyridin-4-ylmethyl...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4854(1-[(4-chlorophenyl)sulfanyl]-4-(pyridin-4-ylmethyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed