BDBM484078 3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)-2- hydroxypropylamino)-1- oxa-8-azaspiro[4.5]decan- 8-ylsulfonyl)- 7-fluoroquinolin-4-ol::US10927123, Compound 329

SMILES O[C@@H](CN[C@H]1COC2(C1)CCN(CC2)S(=O)(=O)c1cnc2cc(F)ccc2c1O)COc1cccc(c1)S(=O)(=O)C1CC1

InChI Key InChIKey=XHTFCTRDBRTXGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484078   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484078(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)
Affinity DataIC50: 2.95E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent