BDBM484059 (S)-1-((S)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-3- ylsulfonyl)-l-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3- (methoxymethylsulfonyl) phenoxy)propan-2-ol::US10927123, Compound 230

SMILES CCOc1ccc(cc1S(=O)(=O)N1CCC2(C[C@@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)COC)CC1)-c1ccc(CN)cc1

InChI Key InChIKey=MWQGFMMWRHXINT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484059   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484059((S)-1-((S)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent