BDBM483719 1-(5-(2,5- dichlorobenzyl)- octahydropyrrolo- [3,4-c]pyrrole-2- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 202::US11655217, Example 202

SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cc(Cl)ccc3Cl)CC2C1

InChI Key InChIKey=JKMBANCAVKXCGQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483719   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483719(US10927105, Ex 202 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483719(US10927105, Ex 202 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483719(US10927105, Ex 202 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483719(US10927105, Ex 202 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In DepthDetails
US Patent