BDBM482217 N-{3-[4-Amino-7-(1-methyl-piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-fluoro-phenyl}-3,4-dichloro-benzenesulfonamide ::US10918642, Cmpd # 71::US11491158, Cmpd 71

SMILES CN1CCC(CC1)n1cc(-c2cccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c2F)c2c(N)ncnc12

InChI Key InChIKey=MYVSOMJEFDKSDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482217   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM482217(US10918642, Cmpd # 71 | N-{3-[4-Amino-7-(1-methyl-...)
Affinity DataIC50: 16nMAssay Description:Compounds were 3-fold serially diluted in order to obtain from 3.333 to 0.000169 microM final concentration, then incubated for 60 minutes at room te...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEukaryotic translation initiation factor 2-alpha kinase 3 [540-1115](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM482217(US10918642, Cmpd # 71 | N-{3-[4-Amino-7-(1-methyl-...)
Affinity DataIC50: 16nMAssay Description:The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111...More data for this Ligand-Target Pair
In DepthDetails
US Patent